Figure 2 | Molecular Psychiatry

Figure 2

From: Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate

Figure 2

Manhattan plot illustrating the independently analyzed endophenotypes with age and sex as covariates for chromosomal regions 4q, 5q, 11p, 17p and 20q. The vertical axis represents –log10(P-value); –lg(P)>1.30 was defined as a significant association. ROCFT copy was highly associated with LPHN3 variants harbored in the same region associated to ADHD. ACVTCR, <<A>> Cancellation and Vigilance Test copy response; ACVTO, <<A>> Cancellation and Vigilance Test Omissions; ROCFT_copy, Rey-Osterrieth Complex Figure Test Copy subtest; WISC_FSIQ, Wechsler Intelligence Scale for Children Full Scale Intelligence Quotient; WISC_PIQ, Wechsler Intelligence Scale for Children Performance Intelligence Quotient; WISC_block, Wechsler Intelligence Scale for Children Block Design.

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