Table 1 Patients’ demographics and clinical characteristics

From: A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients

 

Pooled placebo (n=6) N (%)

40 mg q.d. (n=6) N (%)

40 mg b.i.d. (n=6) N (%)

40 mg t.i.d. (n=6) N (%)

P

Ethnic origin, n (%)

 Caucasian

4 (66.6)

3 (50.0)

2 (33.3)

2 (33.3)

0.604a

 African American

0 (0.0)

2 (33.3)

3 (50.0)

2 (33.3)

 

 Hispanic

2 (33.3)

1 (16.6)

1 (16.6)

1 (16.6)

 

 Asian

0 (0.0)

0 (0.0)

0 (0.0)

1 (16.6)

 

Gender, n (%)

    

0.262a

 Male

5 (83.3)

2 (33.3)

3 (50.0)

2 (33.3)

 

 Female

1 (16.6)

4 (66.6)

3 (50.0)

4 (66.6)

 

Age (year), mean (s.d.)

28.20 (4.75)

34.00 (3.50)

38.50 (12.94)

40.50 (9.92)

0.098b

MADRS total score at screening, mean (s.d.)

25.20 (2.93)

26.00 (3.35)

26.83 (2.64)

24.83 (2.56)

0.636b

  1. Abbreviation: ANOVA, analysis of variance.
  2. aStatistical method used, χ2 test.
  3. bStatistical method used, one-way ANOVA.