Table 2 Descriptive data for the distribution of individuals across non-twin full-siblings (n=2 369 775), DZ twins (n=27 148) and MZ twins (n=12 588) nested within the patient groups in the sample used for the quantitative genetic models
Schizophrenia (n=5549; 0.3%) | Bipolar disorder (n=7509; 0.4%) | |||||
|---|---|---|---|---|---|---|
Non-twin full-siblings | DZ twins | MZ twins | Non-twin full-siblings | DZ twins | MZ twins | |
Socio-demographic factors | ||||||
Age at 1st diagnosis, years (s.e.m.) | 28.1 (7.6) | 29.1 (7.6) | 29.7 (8.8) | 31.4 (8.6) | 32.1 (9.0) | 32.2 (9.3) |
Female, n (%) | 1906 (35.3) | 40 (36.7) | 13 (39.4) | 4,503 (61.6) | 91 (63.2) | 39 (68.4) |
Immigrant background, n (%) | 52 (1.0) | 2 (1.8) | 3 (9.1) | 18 (0.2) | 1 (0.7) | 0 |
Income in the lowest decile, n (%) | 741 (13.7) | 17 (15.6) | 6 (18.2) | 766 (10.5) | 24 (16.7) | 4 (7.0) |
Single, n (%) | 3795 (91.8) | 77 (90.6) | 27 (90.0) | 4,515 (67.0) | 87 (64.4) | 33 (66.0) |
Died during follow-up, n (%) | 476 (8.8) | 8 (7.3) | 0 | 247 (3.4) | 5 (3.5) | 2 (3.5) |
Emigrated during follow-up, n (%) | 163 (3.0) | 2 (1.8) | 0 | 286 (3.9) | 5 (3.5) | 0 |
Lifetime comorbidities | ||||||
Substance misuse, n (%) | 1514 (28.0) | 28 (25.7) | 7 (21.2) | 1,919 (26.3) | 37 (25.7) | 13 (22.8) |
Violent crime, n (%) | 1173 (21.7) | 19 (17.4) | 9 (27.3) | 764 (10.5) | 14 (9.7) | 7 (12.3) |
Number of patients | 5407 | 109 | 33 | 7308 | 144 | 57 |
Prevalence (95% CI) | 0.3% (0.3–0.3%) | 0.4% (0.3–0.5%) | 0.3% (0.2–0.4%) | 0.4% (0.4–0.4%) | 0.5% (0.4–0.6%) | 0.5% (0.3–0.6%) |
