Table 4 Age- and sex-adjusted polygenic risk score associations with BMI and general cognitive function

From: Assessing the genetic overlap between BMI and cognitive function

 

n

Beta a

s.e.

P-value

General cognitive function polygenic score b

 General cognitive function

6273

0.090

0.01

3.3 × 10−13

 BMI

6463

−0.029

0.01

0.020

BMI polygenic score b

 General cognitive function

6273

−0.065

0.01

1.9 × 10−7

 BMI

6463

0.266

0.01

<2 × 10−16

  1. Abbreviation: BMI, body mass index.
  2. aThe dependent variable and continuous independent variables were standardised in the regression models.
  3. bPolygenic risk scores were adjusted for age, sex and 14 multi-dimensional scaling components with residuals taken forward as the independent variable of interest.
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