Figure 3
Heatmap representing subpopulations of receptors, neurotransmitters and transporters in all subregions of the BNST. Adapted from the study by Bota et al.60 with the following genes added: DARPP32,71 CGRP,71 VIP,71 PAC1,63 PACAP,63, 64 CRFR1,81 CRFR2,67, 81 PR,68, 69 A1-Adr,62, 96 A2-Adr,62, 65 B1-Adr,53, 62, 65 B2-Adr.62, 65 The original data were extracted from the study by Bota et al.60 which categorized the expression levels from 0 to 9, with 12 having no data. In our version, we binned all the genes previously published and newly added from 0 to 3, 4 to 6, 6 to 9 and no data into 4 ranks of strong, moderate, weak expression and no data to combine all the data into the qualitative expression heatmap. A1-Adr, adrenergic receptor alpha-1; A2-1 GABA A, GABRA2, GABA a2 receptor; A2-Adr, adrenergic receptor alpha-2; A3-1 GABA A, GABA3, GABA a3 receptor, B1-1 GABA A, GABA beta 1 receptor; AII, angiotensin I; AR, androgen receptor; AVP, vasopression; B1-Adr, adrenergic receptor beta 1; B2-Adr, adrenergic receptor beta 2; B3-1 GABA A, GABA beta 3 receptor; CaB, calbindin; CB-1R, cannabinoid receptor 1; CCK, cholecystokinin; CGRP, calcitonin gene-related peptide; ChAT, choline acetyltransferase; CR, calretinin; CRFR1, cortiotrophin releasing factor receptor type 1; CRFR2, corticotrophin-releasing factor, receptor type 2; D1, Drd1A, dopamine receptor type 1A; D2, Drd2A, dopamine receptor type 2A; DARPP32, dopamine- and cAMP-regulated phosphoprotein; DOR, delta opioid receptor; DYN, dynorphin; ENK, enkelphalin; ER, estrogen receptors; G1-1 GABA A, GABA, gamma 1 receptor; GAD65, glutamate decarboxylase 65; GAD67, glutamate decarboxylase 67; GAL, galanin; GluR7, GRIK3, kainate receptor; GlurR5, GRIK1 kainate receptor; Htr1A, 5Ht1A, serotonin receptor type 1; KA2, GRIK 5, kainate receptor; KOR, kappa-opioid receptor; mGluR2, metabotropic glutamate receptor 2; mGluR7A, metabotropic glutamate receptor 7A; mGluR7B, metabotropic glutamate receptor 7B; MOR, mu-opioid receptor; nChR, nicotinic acetylcholine receptor; NK3, tachykinin receptor 3; NKB, neurokinin B; NPY, neuropeptide Y; NPY1, neuropeptide Y receptor Y1; NPY2, neuropeptide Y receptor Y2; NPY4, neuropeptide Y receptor Y4; NPY5, neuropeptide Y receptor Y5; NT, neurotensin; Oxt-1A, oxytocin receptor 1A; Oxt-1B, oxytocin receptor 1B; PAC1, Adcyap1r1, pituitary adenylate cyclase-activating polypeptide type 1; PACAP, pituitary adenylate cyclase-activating polypeptide; PR, progesterone receptor; SOM, somatostatin; SP, substance P; VGLUT1, vesicular glutamate transporter 1; VGLUT2, vesicular glutamate transporter 2; VGLUT3, vesicular glutamate transporter 3; VIP, vasoactive intestinal peptide.
