Figure 3
From: The PHF21B gene is associated with major depression and modulates the stress response
Animal studies. (a) Paired t-test showed significantly increased floating time between the first (T1, baseline) and the second (T2, post-CRS) forced swim tests (FST) in the chronic restraint stress (CRS) non-resilient (nonresil, n=8) group but not in the CRS resilient (resil, n=11) and the non-CRS (n=6) groups. (b) One-way ANOVA showed that hippocampal Phf21b gene expression was significantly decreased in the CRS resil (resilient) group (n=11) but not in the CRS nonresil (non-resilient) group (n=8) comparing with the non-CRS group (n=6); columns=mean, bars=standard deviation of the mean. (s), seconds; AU, arbitrary units; **P<0.01; ***P<0.001.
