Figure 4
Scatter plots of streamline count as a function of age for the network-based statistic (NBS)-derived subnetworks. Each data point represents the total streamline counts for each subject within the significant NBS networks. (a) CN>HR network 1, (b) CN>HR network 2, (c) CN<HR network and (D) CN>BD network. Solid lines show the best-fitting nonlinear (quadratic) regression function of age overall across the groups. Although all four curves appear to show a negative (nonlinear) effect of age, the null hypothesis of a simpler linear model was not rejected for any of the networks (P>0.19, false discovery rate-corrected). BD, bipolar disorder; CN, controls; HR, high risk.
