Table 2 Results of gene analysis (top 20 genes)
Symbol | Gene name | Chr | Start | Stop | SNPs | Parameters | N | Z stat | P-value |
|---|---|---|---|---|---|---|---|---|---|
WNT3 | Wingless-type MMTV integration site family, member 3 | 17q21.31 | 44836686 | 44901082 | 127 | 46 | 29 063 | 5.4753 | 2.18E−08 |
PLEKHM1 | Pleckstrin homology and RUN domain-containing M1 | 17q21.31 | 43508266 | 43573146 | 123 | 23 | 27 885 | 4.9724 | 3.31E−07 |
TP53 | Tumor protein p53 | 17p13.1 | 7566720 | 7595863 | 94 | 32 | 31 813 | 4.9082 | 4.60E−07 |
ARHGAP27 | Rho GTPase-activating protein 27 | 17q21.31 | 43466268 | 43515282 | 128 | 17 | 25 183 | 4.8923 | 4.98E−07 |
CYB561D1 | Cytochrome b561 family, member D1 | 1p13.3 | 110031658 | 110048063 | 27 | 12 | 31 670 | 4.7687 | 9.27E−07 |
WRAP53 | WD repeat containing, antisense to TP53 | 17p13.1 | 7584389 | 7611820 | 63 | 20 | 32 133 | 4.6221 | 1.90E−06 |
ATXN7L2 | Ataxin 7-like 2 | 1p13.3 | 110021561 | 110040426 | 29 | 11 | 33 153 | 4.5842 | 2.28E−06 |
PSMA5 | Proteasome subunit alpha 5 | 1p13.3 | 109936653 | 109974108 | 62 | 23 | 32 881 | 4.4835 | 3.67E−06 |
NSF | N-ethylmaleimide sensitive factor | 17q21.31 | 44663035 | 44839830 | 89 | 20 | 29 574 | 4.4412 | 4.47E−06 |
SORT1 | Sortilin 1 | 1p13.3 | 109847187 | 109945563 | 147 | 36 | 33 175 | 4.4403 | 4.49E−06 |
SYPL2 | Synaptophysin-like 2 | 1p13.3 | 110004100 | 110029764 | 66 | 16 | 34 387 | 4.4171 | 5.00E−06 |
CFAP99 | Cilia- and flagella-associated protein 99 | 4p16.3 | 2415701 | 2469690 | 171 | 43 | 33 195 | 4.3569 | 6.60E−06 |
KANSL1 | KAT8 regulatory NSL complex subunit 1 | 17q21.31 | 44102282 | 44307740 | 775 | 22 | 27 788 | 4.3536 | 6.70E−06 |
STH | Saitohin | 17q21.31 | 44071616 | 44082060 | 56 | 12 | 26 909 | 4.3028 | 8.43E−06 |
SPPL2C | Signal peptide peptidase-like 2C | 17q21.31 | 43917256 | 43929438 | 69 | 8 | 30 906 | 4.2974 | 8.64E−06 |
SP140L | SP140 nuclear body protein like | 2q37.1 | 231186894 | 231273445 | 365 | 51 | 34 250 | 4.1532 | 1.64E−05 |
LRRC37A | Leucine-rich repeat containing 37A | 17q21.31 | 44367497 | 44420160 | 5 | 3 | 26 694 | 4.1414 | 1.73E−05 |
MAPT | Microtubule-associated protein tau | 17q21.31 | 43966748 | 44110700 | 725 | 33 | 29 040 | 4.079 | 2.26E−05 |
CRHR1 | Corticotropin-releasing hormone receptor 1 | 17q21.31 | 43692710 | 43918194 | 1024 | 75 | 30 191 | 3.7486 | 8.89E−05 |
PCDH15 | Protocadherin-related 15 | 10q21.1 | 55557531 | 56566051 | 4082 | 531 | 33 480 | 3.218 | 6.46E−04 |
