Figure 3
From: Cannabis use and risk of schizophrenia: a Mendelian randomization study

Comparison of observational (blue) and causal (red) estimates for use of cannabis and risk of schizophrenia. Two observational estimates are provided according to a stringent definition of schizophrenia (as reported in the Swedish cohort16) or to an outcome comprising studies reporting risk of schizophrenia or psychotic symptoms (derived from the meta-analysis reported in Figure 1) for ever use of cannabis. Causal estimates represent population-based associations derived by conventional (Figure 2) and multivariable Mendelian randomization (MR). The total number of cases and controls in each analysis are presented.