Figure 4
Bivariate correlations in patients with Alzheimer’s disease from ROS/MAP (n=243) stratified by rs73069071 genotype between: (a) brain Aβ deposition (quantitative composite score computed by averaging the percent areas occupied by Aβ across eight brain regions, as measured by immunohistochemistry; Correlations among regional percent areas occupied by Aβ across these brain regions are illustrated in Supplementary Figure 1) and global cognitive function; (b) diffuse (top) and neuritic (bottom) brain Aβ deposition (quantitative composite scores computed by averaging standardized regional densities across 5 brain regions) and global cognitive function; and (c) diffuse and neuritic brain Aβ deposition. Rs73069071CC and rs73069071TC carriers are grouped together for the purpose of visualization.
