Figure 1

(a) Manhattan and (b) Q–Q plots of P-values of the SNP-based association analyses for each of the cognitive phenotypes: educational attainment, verbal–numerical reasoning, reaction time and memory. The red line indicates the threshold for genome-wide significance (P<5 × 10−8); the grey line indicates the threshold for suggestive significance (P<1 × 10−5). SNP, single-nucleotide polymorphism.