Figure 2
From: Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition
Caspase-1 (casp1) deficiency increases spontaneous locomotion and locomotory skills. (a) Casp1 knockout (casp1−/−) mice had increased locomotor activity in the open field test when compared with wild-type (wt) mice and (b) acquired quicker the skills to perform the rotarod test. Data are mean±s.e.m. Genotype effect: P<0.05; **P<0.01; ****P<0.0001. BL, baseline; STR, after chronic restraint stress paradigm.
