Figure 2 | Molecular Psychiatry

Figure 2

From: Vortioxetine reduces BOLD signal during performance of the N-back working memory task: a randomised neuroimaging trial in remitted depressed patients and healthy controls

Figure 2

Vortioxetine reduced blood-oxygen-level-dependent (BOLD) signal within (a) the right dorsolateral prefrontal cortex (dlPFC) and (b) left hippocampus across all participants. Red voxels show significant difference (cluster corrected P<0.05) between treatment groups in the change of N-back–0-back contrast across treatment within the prespecified anatomical masks across all subjects. Bar charts illustrate the mean (±s.e.m.) of the extracted signal change separated by treatment and subject group.

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