Figure 4
From: Precision medicine for suicidality: from universality to subtypes and personalization

Convergent Functional Information for Suicide (CFI-S) testing. Testing in a large cohort that combines the discovery and test cohorts used for biomarker work. CFI-S was developed independently of any data from this study, by compiling known socio-demographic and clinical risk factors for suicide. It is composed of 22 items that assess the influence of mental health factors, as well as of life satisfaction, physical health, environmental stress, addictions and cultural factors known to influence suicidal behavior, as well as two demographic factors, age and gender. (a) Prediction of high suicidal ideation (HAMD SI>=2). (b) Prediction of future hospitalizations due to suicidality within one year of follow-up. Table under a depicts individual items and their ability to differentiate between participants with No SI, Intermediate SI and High SI. Stepwise refers to gradual increase between the three groups (No SI, Intermediate SI, High SI). Table under b depicts individual items and their ability to differentiate between participants with and without future hospitalizations due to suicidality. Different items are positive in different individuals, providing leads for targeted (psycho)therapeutic interventions.