Table 1 Summary of module characterization and phenotype association
Module | Module size | Genotype | Treatment | Interaction | Gene ontology enrichment | |||||
---|---|---|---|---|---|---|---|---|---|---|
F | P | F | P | F | P | Category | N | P | ||
Black | 300 | 5.87 | 0.042 | 2.63 | 0.144 | 1.17 | 0.312 | Response to organic substance (BP) | 41 | 2.34E−04 |
Blue | 566 | 1.56 | 0.246 | 7.46 | 0.026 | 0.93 | 0.362 | Somitogenesis (BP) | 9 | 9.41E−06 |
Brown | 546 | 2.11 | 0.185 | 10.49 | 0.012 | 1.31 | 0.285 | Negative regulation of JNK cascade (BP) | 5 | 4.65E−04 |
Cyan | 147 | 4.56 | 0.065 | 9.12 | 0.017 | 1.84 | 0.212 | Oxidoreductase activity, acting on NAD(P)H, haem protein as acceptor (MF) | 3 | 6.27E−05 |
Green | 477 | 6.72 | 0.032 | 2.29 | 0.169 | 2.96 | 0.123 | Multicellular organismal development (BP) | 125 | 5.15E−11 |
Green yellow | 172 | 14.46 | 0.005 | 1.11 | 0.323 | 0.00 | 0.981 | Positive regulation of icosanoid secretion (BP) | 3 | 4.64E−05 |
Light cyan | 103 | 0.86 | 0.380 | 11.18 | 0.010 | 3.39 | 0.103 | Extracellular region part (CC) | 16 | 1.30E−05 |
Magenta | 263 | 9.94 | 0.014 | 1.32 | 0.283 | 0.80 | 0.397 | Tricarboxylic acid cycle (BP) | 5 | 5.78E−05 |
Midnightblue | 126 | 4.06 | 0.079 | 8.09 | 0.022 | 2.98 | 0.123 | Negative regulation of cartilage development (BP) | 2 | 1.75E−04 |
Pink | 295 | 0.01 | 0.910 | 14.96 | 0.005 | 0.43 | 0.532 | Positive regulation of interleukin-13 biosynthetic process (BP) | 2 | 4.00E−04 |
Purple | 192 | 0.36 | 0.564 | 13.09 | 0.007 | 0.54 | 0.485 | Negative regulation of peptidyl-threonine phosphorylation (BP) | 2 | 3.85E−03 |
Red | 330 | 1.07 | 0.331 | 6.99 | 0.030 | 0.60 | 0.460 | GTPase regulator activity (MF) | 17 | 1.28E−03 |
Salmon | 167 | 0.00 | 0.985 | 8.78 | 0.018 | 0.30 | 0.599 | Rhythmic process (BP) | 7 | 3.60E−04 |
Tan | 170 | 1.71 | 0.227 | 23.07 | 0.001 | 5.87 | 0.042 | Melanin biosynthetic process from tyrosine (BP)edede | 2 | 1.19E−04 |
Turquoise | 618 | 19.56 | 0.002 | 0.08 | 0.778 | 0.83 | 0.389 | Extracellular region (CC) | 84 | 7.47E−09 |
Yellow | 537 | 0.15 | 0.705 | 11.98 | 0.009 | 0.02 | 0.885 | Enzyme binding (MF) | 67 | 6.56E−06 |