Table 3 Global meta-analysis results

From: Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa

Chr

Pos

Id

Associated gene

EA

NEA

EAF

OR

OR_95L

OR_95U

P

Het_chisq

N_st (discovery/replication)

2

195032811

kgp3754622 (rs75245228)

a

g

0.052

0.81

0.69

0.96

0.016

12.739

8 (6/2)

11

133096498

rs10791286

OPCML

a

g

0.33

0.84

0.78

0.91

9.40 × 10−6

4.228

8 (6/2)

10

53754335

rs1904050

PRKG1

a

g

0.20

0.87

0.79

0.95

0.0018

15.033

7 (5/2)

11

125655014

rs536968

PATE3

a

g

0.12

0.88

0.79

0.98

0.023

12.082

8 (6/2)

10

122659625

exm860538 (rs199965409)

WDR11

a

g

<0.01

10.42

4.40

24.69

9.97 × 10−8

0

1 (1/0)

4

157167891

rs7700147

ANKRD50

t

c

0.21

1.20

1.10

1.30

2.79 × 10−5

9.093

8 (6/2)

6

34826040

exm540361 (rs200155060)

UHRF1BP1

a

g

<0.01

0.18

0.08

0.37

6.47 × 10−6

0

1 (1/0)

6

147840595

rs669830

SAMD5

t

g

0.26

1.11

1.01

1.21

0.029

13.174

5 (3/2)

21

47963149

rs11701571

DIP2A

a

g

0.24

1.11

1.02

1.21

0.011

12.185

6 (4/2)

7

49620107

rs10264162

VWC2

t

g

0.43

0.91

0.84

0.97

0.0068

23.105

8 (6/2)

1

197404688

exm134618 (rs142090517)

CRB1

a

g

<0.01

11.97

4.24

33.81

2.76 × 10−6

0

1 (1/0)

3

150748151

rs1703802

CLRN1-AS1

t

g

0.12

0.84

0.75

0.93

0.00085

7.007

8 (6/2)

17

31082572

exm1310689 (rs145290255)

MYO1D

t

c

0.0011

0.02

0.00

0.10

1.74 × 10−6

0.276

2 (1/1)

4

80949829

exm-rs4333130

ANTRX2

t

c

0.38

0.89

0.83

0.94

7.14 × 10−5

7.526

10 (8/2)

4

26482021

rs2854030

CCKAR

t

c

0.31

0.88

0.78

0.98

0.021

23.181

8 (6/2)

  1. Abbreviations: CHR, chromosome; EA, effect allele; EAF, effect allele frequency; I2, measure of heterogeneity; NEA, non-effect allele; N_st, number of contributing studies; OR, odds ratio; OR_ 95L, lower 95% confidence interval; OR_95U, upper 95% confidence interval; P, P-value; POS, position in hg18.
  2. Gene names given are best-redicted consequence from ensembl,24,25 where none is available; the nearest gene is given instead in bold.