Figure 1: Schematic representation of the P. falciparum 3D7 genome.
From: Genome sequence of the human malaria parasite Plasmodium falciparum
Protein-encoding genes are indicated by open diamonds. All genes are depicted at the same scale regardless of their size or structure. The labels indicate the name for each gene. The rows of coloured rectangles represent, from top to bottom for each chromosome, the high-level Gene Ontology assignment for each gene in the ‘biological process’, ‘molecular function’, and ‘cellular component’ ontologies42; the life-cycle stage(s) at which each predicted gene product has been detected by proteomics techniques14,15; and Plasmodium yoelii yoelii genes that exhibit conserved sequence and organization with genes in P. falciparum, as shown by a position effect analysis. Rectangles surrounding clusters of P. yoelii genes indicate genes shown to be linked in the P. y. yoelii genome165. Boxes containing coloured arrowheads at the ends of each chromosome indicate subtelomeric blocks (SBs; see text and Fig. 2).
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