Figure 4: Matches to CD99 host sequences in P. knowlesi (H strain). | Nature

Figure 4: Matches to CD99 host sequences in P. knowlesi (H strain).

From: The genome of the simian and human malaria parasite Plasmodium knowlesi

Figure 4

a, Seven KIRs show conserved matches to three different regions of CD99 (shown in red, blue and green). b, Schematic view of Macaca mulatta CD99, showing matches to different KIRs. The numbers represent the amino acid position. TM, transmembrane domain. The highlighted regions represent the summary of perfectly matched amino acid stretches in the CD99 extracellular domain to a subgroup of seven KIR proteins. c, Amino acid sequence of Macaca mulatta CD99, highlighting the summary of matches to KIRs. Amino acids corresponding to the transmembrane domain are underlined. The light-grey amino acids represent the transmembrane domain and the intracellular part of CD99. d, Comparison of the matches to Macaca fascicularis, African green monkey and human. Mismatches are highlighted in red. The asterisk refers to an additional host CD99 match in a KIR protein (PKH_031990) that did not satisfy the minimum length cutoff of 15 amino acids.

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