Table 1 PACAP associations with PTSD symptoms
From: Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor
Initial | Replication | Combined | |
|---|---|---|---|
n = 34 | n = 74 | n = 108 | |
**Correlation of PACAP level with PSS hyperarousal score | 0.006 | 0.015 | 0.001 |
*High PACAP level with PSS hyperarousal score (Fig. 1c) | 0.001 | 0.01 | 0.0004 |
*High PACAP level with PSS hyperarousal score (Fig. 1d, adjusted) | 0.01 | 0.001 | 0.00005 |
*High PACAP level with PSS total score (Fig. 1b) | 0.0003 | 0.15 | 0.008 |
*High PACAP level with PSS total score (adjusted) | 0.004 | 0.04 | 0.002 |
*High PACAP level with clinically significant PTSD symptoms (Fig. 1d, adjusted) | 0.0002 | 0.01 | 0.0003 |
*High PACAP levels with PSS-based PTSD diagnosis1 (adjusted) | 0.01 | 0.02 | 0.0008 |
