Figure 2: Transcript and protein variation.
From: Multiple reference genomes and transcriptomes for Arabidopsis thaliana
a, Example of a splice site change between two haplotypes for the gene AT1G64970. Haplotype I (Col-0) is spliced with an intron 6 bp (two amino acids) shorter than haplotype II (Ler-0); Po-0 (heterozygous) shows allele-specific expression of both. b, Re-annotation of the FRIGIDA locus showing annotations for accessions Sf-2 (functional), and Col-0 (truncated by a premature stop) and Ler-0 (non-functional) (Supplementary Figs 18 and 42). Right: the 19 accessions are shown clustered on the basis of the AA distance between their FRIGIDA amino-acid sequences. Common isoform clusters (at distance 2% or less; red line) are shown, leading to three clusters with three, seven and nine accessions. c, Proteome diversity for coding genes, pseudogenes and A. lyrata genes (top) and for genes with disruptions (bottom). Reported is the fraction of genes with relative AA distance to other accessions (average over pairs) in the given colour-coded interval (Supplementary Information section 10.7). d, Frequency of isoforms of coding genes and pseudogenes (top), and those associated with different disruptions (bottom).
