Extended Data Figure 8: Mutation expression and tumour clonal architecture in AML, BRCA and UCEC. | Nature

Extended Data Figure 8: Mutation expression and tumour clonal architecture in AML, BRCA and UCEC.

From: Mutational landscape and significance across 12 major cancer types

Extended Data Figure 8

a, Density plots of expressed VAFs for mutations in SMGs (blue) and non-SMGs (red). b, SciClone clonality example plots for AML (validation data), BRCA and UCEC. Two plots are shown for each case: kernel density (top), followed by the plot of tumour VAF by sequence depth for sites from selected copy number neutral regions. Mutations (with annotations) in SMGs were shown.

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