Extended Data Figure 5: Correspondence between individual subunits and anthropomorphic features of the eIF3 core complex and three-dimensional variance of the 40S–DHX29–ΔII-IRES–eIF3 map.
From: Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
a, b, Front (upper panels) and back views (lower panels) of cryo-electron microscopy reconstructions of eIF3 as it appears in class 4 of the CSFV ΔII-IRES–40S–DHX29–eIF3 complex bound to the CSFV ΔII-IRES (a) and alone13 (b), labelled to show anthropomorphic terms12 and the localization of individual subunits in the core complex11,24. c, three-dimensional variance of the class 4 cryo-electron microscopy map, filtered to 20 Å, and coloured according to the computed three-dimensional variance (see Methods), from dark blue for the lowest variance to red for the highest variance. The map is filtered to the resolution at which the three-dimensional variance was estimated (∼20 Å).
