Extended Data Figure 9: Cryo-EM densities of selected regions of TRPV1 at 3.4 Å resolution.
From: Structure of the TRPV1 ion channel determined by electron cryo-microscopy
a–d, Representative cryo-EM densities (grey mesh) are superimposed on atomic model (main chain in pink) for various TRPV1 domains, as indicated. e, f, Representative cryo-EM densities (grey mesh) are docked with crystal structure of TRPV1 ankyrin repeats (PDB 2PNN). Accuracy of docking was supported by fitting of several bulky side chains. Map was low-pass filtered to 3.4 Å and amplified by a temperature factor −100 Å2.
