Extended Data Figure 4: The spatial distribution of Confetti clone expansion within the stem-cell niche.

a, b, Spatial distribution of confetti clones, subdivided into clones starting in the central (a) or border (b) region (n = 4 mice). Top left panel (a) shows the relative Confetti⁺ cell position within the stem-cell niche, where row 0 to +4 translates to z0 to z13 of the z-stack. Every table shows the number of Confetti-labelled cells that are present at the different positions in the crypt, independent of Lgr5 expression. The position within the central and border region of the stem-cell niche and TA compartment are colour coded. The hash symbol indicates the presence of Confetti-labelled cells in the TA compartment. NA indicates time points for which data was not available owing to crypts that were not retraceable at that specific time point.