Extended Data Table 1 Relationships between poly(A)-tail lengths of orthologous genes in samples from different species (or the same gene, when the samples are from the same species), and relationships between poly(A)-tail length and the indicated mRNA features

From: Poly(A)-tail profiling reveals an embryonic switch in translational control

  1. When calculating splice-site density, a pseudocount of one was added to the number of splice sites in an mRNA. For the comparisons between poly(A)-tail length and expression level, mRNA abundances were measured by RNA-seq; data for HeLa were from ref. 35. For the relationship between poly(A)-tail length and mRNA nuclear-to-cytoplasmic abundance ratio, measurements of nuclear and cytoplasmic mRNA abundance in HeLa cells were from ref. 47. mRNA half-lives for S. cerevisiae, HeLa and 3T3 mRNAs were from refs 48, 49, 50, 51, 52, 53, 54, 55, ref. 56 and ref. 31, respectively.
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