Extended Data Figure 5: Viral load measurements over time after passive antibody transfer and SHIV challenge of non-human primates.
From: Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
The indicated monoclonal antibodies (0.3 mg kg−1) were administered intravenously to rhesus macaques (n = 12). Macaques were challenged with SHIV BaLP4 5 days later, and the plasma viral loads were measured over time. Normal human IgG was given to the control group. Five of 12 VRC01-LS-injected macaques and 10 of 12 VRC01-injected macaques were infected (P = 0.0447, one-tailed Fisher’s exact test).
