Extended Data Figure 10: Dietary modulation of the intestinal microbiota composition drives autoinflammatory osteomyelitis by setting pro-IL-1β levels available for maturation by caspases 1 and 8.
From: Dietary modulation of the microbiome affects autoinflammatory disease
Proposed model highlighting how dysbiosis and processing of IL-1β by caspases 1 and 8 contribute to the development of inflammatory bone disease.
