Extended Data Figure 9: H. pylori infection of hGOs.
From: Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
a, hGOs were used to model human-specific disease processes of H. pylori infection. Bacteria were microinjected into the lumen of hGOs and bacteria were detected in the lumen 24 h after injection by bright-field microscopy (black arrow). b, Electron micrograph illustrating the attachment of an H. pylori bacterium to an hGO epithelial cell 24 h after injection. Scale bar, 500 nm. c, Western blots from Fig. 4 that show the molecular mass markers in the first lane. The darker exposure for the CagA western blot (CagA dark) was included to show the molecular mass markers (170 and 130 kDa).
