Extended Data Figure 6: Recognition of the vRNA 3′ end.
From: Structure of influenza A polymerase bound to the viral RNA promoter
Protein interactions of the distal 3′ end showing the role of PB2-Nter (red). PB2 residues Arg 46 and Trp 49 and PA residue Lys 567 stabilize the sharp turn between 3′ nucleotides C8 and G9. PB2 Arg 38 and PB1-Cter residues Asn 671, Arg 672 and Asn 676 also bind the 3′ end. In the accompanying paper18, Fig. 2a shows the interactions with the complete 3′ end as observed in the FluB vRNA complex.
