Extended Data Figure 6: Chemokine expression patterns indicate that CCL4 expression from tumour cells is directly inhibited by active β-catenin-signalling.
From: Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
a, Expression of Ccl4 mRNA in established tumour cell lines BP and BPC (8 independent experiments). b, Amount of secreted CCL4 in 48 h conditioned BP and BPC tumour cell supernatants, assessed by ELISA (4 independent experiments). c, d, Control qRT–PCR for the experiment shown in Fig. 4e with Ifnb expression (c) and Ifng expression (d) (n = 6). ND, not detected. All data are mean ± s.e.m., Mann–Whitney U test. *P ≤ 0.05.
