Extended Data Figure 1: Correlation between active β-catenin and CD8 T-cell infiltrate in human patients.
From: Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
a, A continuous numerical score was generated using six β-catenin target genes (CTNNB1 score). Using this score, patients from the TCGA data set were grouped in high or low CTNNB1 score (centred on the average score) (low, 91 patients; high, 108 patients). Subsequent correlation analysis was performed using a Fisher’s exact test. b, Representative examples for CD8 and β-catenin staining in human needle biopsies used for analysis shown in Fig. 1d.
