Extended Data Figure 6: The decoding centre on the 40S.
a, Contact regions of the E-site tRNA on the 40S subunit. b, Catalytic PTC region of the ribosome, highlighting the partial structural disorder of a region of protein uL16 (loop), and disorder of residue U4548 (28S rRNA) in the absence of P-site tRNA, while all other residues are well-ordered. This suggests that the P-site pocket is largely pre-defined while U4548 and the loop participate in tRNA accommodation.
