Extended Data Figure 7: Refined maximum likelihood phylogeny of two GPCRs expressed in the PPE-derived neurons of Ciona intestinalis. | Nature

Extended Data Figure 7: Refined maximum likelihood phylogeny of two GPCRs expressed in the PPE-derived neurons of Ciona intestinalis.

From: The pre-vertebrate origins of neurogenic placodes

Extended Data Figure 7

Relative to the initial survey tree (see Extended Data Fig. 6), analysis of this focused set of ‘chemokine cluster’ sequences further clarifies the phylogenetic affinities of two Ciona GPCRs expressed in the aATEN–GnRH neurons. The latter sequences are highlighted with violet boxes; all other Ciona sequences are from Kamesh et al.37. The three nodal support values are (in order): ME bootstrap percentage, ML bootstrap percentage and BI posterior probability (only values >50 are shown). Branch lengths are proportional to molecular change (amino acid substitutions per site) between nodes; see scale bar for measurement.

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