Extended Data Table 1 Statistical comparison for orientation bias and resection in Sγ1 and Sε junctions from wild-type and DSBR-deficient B cell libraries

From: Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching

  1. a, b, P values calculated by unpaired two-tailed t-test for the degree of bias in the Sγ1 (a) and Sε (b) junctions between wild-type and DSBR-deficient B cells with full-length Sμ for experiments described in Figs 3 and 4. Orientation bias was calculated as described in the Methods for individual libraries. Numbers in parenthesis indicate independent experiments performed for each genotype. N/A, not available. c, d, P values calculated by unpaired two-tailed t-test for the level of resections in the Sγ1 (c) and Sε (d) junctions for experiments described above. Percentage of resection was calculated as described in the Methods for individual libraries. Numbers in parenthesis indicate independent experiments performed for each genotype. Ai, ATM inhibitor.
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