Extended Data Figure 4: Gsdmd cleavage site.
From: Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
a, Alignment of Gsdmd amino acid sequences. The conserved Gsdmd cleavage site (D276 in mouse) is boxed in red. b, Immunoblots of BMDM extracts and supernatants at 16 h after LPS/Ctb treatment. A non-specific band is indicated with an asterisk. Cont, Ctb alone. For source gel, see Supplementary Fig. 3.
