Extended Data Figure 6: Effects of p16^INK4a silencing in autophagy-impaired young murine satellite cells.

a, Western blotting quantification of Atg7^ΔPax7 satellite cells, infected with lentiviral LV-sh-p16^INK4a or LV-sh-scramble and analysed 96 h later; for full gel scan see Supplementary Fig. 2. b, Atg7^WT and Atg7^ΔPax7 EDL, infected with LV-sh-p16^INK4a or LV-sh-scramble, and grafted as Extended Data Fig. 2j. Representative eMHC-immunostaining. Scale bar, 25 μm. Data show mean ± s.e.m. Comparisons by two-sided Mann–Whitney U-test. P values are indicated. The number of samples were n = 3 animals per group (a) and n = 4 engraftments per group (b).