Extended Data Figure 4: Mitochondrial morphology of bone marrow populations.

a, Representative images of mitochondrial morphology in Pham-reporter⁺ CD150^hi and CD150^lo HSCs (lin⁻Sca1⁺kit⁺Flt3⁻CD48⁻), MPPs (lin⁻Sca1⁺kit⁺CD48⁺), CMPs (lin⁻Sca1⁻kit⁺), CLPs (lin⁻Sca1^lokit^loIL7Ra⁺Flt3⁺) and lineage⁺ cells (scale bar, 5 μm). b, Mitochondrial length frequency distribution in Pham-reporter⁺ HSCs, progenitors and Lin⁺ cells. Bars, mean ± s.e.m.; n ≥ 14 fields from three biological replicates; *P < 0.05 within length bins; one-way ANOVA with Bonferroni’s post-hoc test within length bins.

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