Extended Data Table 1 Phenotypic analysis of the haematopoietic system in Mfn2fl/fl-Vav-Cre mice

From: Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential

  1. a–f, Analysis of 8–10 week-old Mfn2fl/fl or Mfn2fl/fl-Vav-Cre mice for (a) frequency of LSK cells and HSCs, (b) peripheral blood counts, (c) bone marrow progenitor populations (MPPs (lin−Sca1+kit+CD48+), CMPs (lin−Sca1−kit+), CLPs (lin−Sca1lokitloIL7Ra+Flt3+), MEPs (Lin−Kit+Sca1−CD16/32lowCD34−)), (d) myeloid (Gr1+/Mac1+), T (CD3+) and B (CD19+) cells in the spleen, (e) myeloid (Gr1+/Mac1+), T (CD3+) and B (CD19+) cells in peripheral blood mononuclear cells, and (f) thymocyte subpopulations (DP: CD4+CD8+, DN: CD4−CD8−, DN1: CD4−CD8−CD44+CD25−, DN2: CD4−CD8−CD44+CD25+, DN3: CD4−CD8−CD44−CD25+, DN4: CD4−CD8−CD44−CD25−). Data are mean ± s.e.m.; n = 3 mice; *P < 0.05; two-tailed Student’s t-test.
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