Extended Data Table 2 Sequence-specific assignment 1H–15N valine resonances

From: Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

  1. Ate, atenolol; Alp, alprenolol; Iso, isoprenaline; Dob, dobutamine; Car, carvedilol; Cya, cyanopindolol
  2. HN(CO): information from 2D-filtered HN(CO) of [15N,13C]Gly,Val-, [15N]Leu-labelled receptor
  3. Pred: ShiftX2 15N chemical shift prediction31
  4. HB: expected 1HN shift based on hydrogen bond length analysis
  5. NM: peak shift due to mutation of neighbouring residue
  6. Assignments for V89(2.52), V95(2.57), V103(2.65), V122(3.33), and V165(4.49) are tentative. V51(1.42), V52(1.43), V56(1.47), V60(1.51), V309(6.54), V312(6.57), and V320(ECL) have not been assigned.
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