Extended Data Figure 1: PD-L1 SVs affecting 3′-UTR in ATL.
From: Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers
a, Diagram showing numbers of ATL samples investigated by WGS/RNA-seq. b, Genome-wide distribution of SV (without deletion) breakpoints in 49 ATL samples, showing a prominent peak at the PD-L1 locus. c, Summary of different types of SVs commonly affecting 3′ region of the PD-L1 gene are shown by indicated colours. d, 3′-truncated PD-L1 mRNA transcripts observed in ATL cases. RNA-seq data are visualized by IGV for ATL samples with or without PD-L1 SVs. Aberrant PD-L1 transcripts are shown in red.
