Extended Data Figure 7: Bioinformatic analysis of proteins enriched in the high-salt fraction upon protein VII expression.
From: A core viral protein binds host nucleosomes to sequester immune danger signals
a, Venn diagram showing overlap between three biological replicates of high-salt-fraction proteins significantly enriched compared with uninduced cells. b, Proteins found significantly enriched in the protein-VII–HA-induced state compared with uninduced (<5% homoscedastic t-test) in all three biological replicates (‘VII–HA induced’ indicates proteins identified only in protein-VII–HA-induced condition). c, d, Classification of proteins significantly enriched in minimum two out of three biological replicates (protein-VII–HA-induced versus uninduced) according to process network enrichment and Gene Ontology biological process (GeneGo MetaCore pathways analysis package; false discovery rate (FDR) < 5%); each Gene Ontology term was ranked using P-value enrichment.
