Extended Data Figure 7: qPCR quantification of MYCN and let-7 copies per cell.
From: Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma
a, Total let-7 sites per cell provided by MYCN mRNA in BE(2)C, Kelly, normal human fibroblasts (NHF), and embryonic carcinoma cells (EC) (mean plus s.e.m. of three biological replicates shown). b, Total let-7 copies per cell in cells from a, presented as stacked graphs of all let-7 family members (mean of three biological replicates shown). c, Total let-7 copies per cell in wild-type or LIN28B knockout BE(2)C and Kelly cells, presented as stacked graphs of all let-7 family members (values derived from let-7 copies per cell in b and average let-7 fold change described in Fig. 2f, g).
