Extended Data Figure 4: Structure-based alignment of eIF3d cap-binding domain and DXO cap-endonuclease domain sequences.
From: eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
Structure-based alignment of eIF3d and DXO sequences according to superposition of eIF3d and DXO (PDB 4J7L) structures15. Alignment is coloured by phylogenetic conservation as in Extended Data Fig. 2, and cartoon schematics of the secondary structures are depicted below the sequences. eIF3d is coloured in blue and magenta as in Fig. 2, and DXO is coloured in green and magenta.
