Extended Data Figure 4: MSMC genetic split times and outgroup f3 results.
From: Genomic analyses inform on migration events during the peopling of Eurasia
a, The MSMC split times estimated between each sample and a reference panel of nine genomes were linearly interpolated to infer the broader square matrix. b, c, Summary of outgroup f 3 statistics for each pair of non-African populations or an ancient sample using Yoruba as an outgroup. Populations are grouped by geographic region and are ordered with increasing distance from Africa (left to right for columns and bottom to top for rows). Colour bars at the left and top of the heat map indicate the colour coding used for the geographical region. Individual population labels are indicated at the right and bottom of the heat map. The f3 statistics are scaled to lie between 0 and 1, with a black colour indicating those close to 0 and a red colour indicating those close to 1. Let m and M be the minimum and maximum f3 values within a given row (that is, focal population). That is, for focal population X (on rows), m = minY,Y≠X f3(X, Y; Yoruba) and M = maxY,Y≠X f3(X, Y; Yoruba). The scaled f3 statistic for a given cell in that row is given by f3scaled = (f3 − m)/(M − m), so that the smallest f3 in the row has value f3scaled = 0 (black) and the largest has value f3scaled = 1 (red). By default, the diagonal has value f3scaled = 1 (red). The heat map is therefore asymmetric, with the population closest to the focal population at a given row having value f3scaled = 1 (red colour) and the population farthest from the focal population at a given row having value f3scaled = 0 (black colour). Therefore, at a given row, scanning the columns of the heat map reveals the populations with the most shared ancestry with the focal population of that row in the heat map.
