Extended Data Table 3 Mutual exclusiveness pairs in prostate cancer

From: Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer

  1. Gene A (PTEN, TP53, SMAD4 and RB1) represents the most common altered tumour suppressors in prostate cancer. For each gene in the Gene B list the table shows: (1) mutual exclusiveness score (odds ratio score) with Gene A; (2) Gene B expression in Gene A-deleted prostate cancer samples (P < 0.1); and (3) proposed functions in cancer progression. P values were determined by two-tailed t-test.
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