Extended Data Table 3 Within-sample variant validation between and within sequencing methods

From: Zika virus evolution and spread in the Americas

  1. a, For each method (amplicon sequencing or hybrid capture), fraction of identified variants (≥1%) not identified at ≥1% by the other method (that is, unvalidated). ‘Verified’ hybrid capture variants are those passing strand bias and frequency filters, as described in Methods. b, For each method, the fraction of identified variants unvalidated in a second library. To pass the strand bias filter, a variant must meet filter criteria in both replicates.
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