Extended Data Table 3 Genomic inflation

From: Fine-mapping inflammatory bowel disease loci to single-variant resolution

  1. Genomic inflation factors and linkage disequilibrium score regression intercept for Crohn’s disease (CD), ulcerative colitis (UC) and both (IBD). a, Genomic inflation factors using the first four, five, and six principal components. The factors were calculated using 2,853 background variants from the ImmunoChip. b, Genomic inflation factors for subsets of the data (using five principal components for the same 2,853 background variants). Balanced, imbalanced, and down-sampled cohorts are defined in Methods. Numbers in brackets indicate the 95% confidence interval for the inflation factors (only estimated for the down-sampled cohorts). c, Linkage disequilibrium score regression intercept and genomic inflation factors (λGC and λ1000) from the largest IBD meta-analyses with genome-wide data (CD: GWAS and UC: GWAS).
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