Extended Data Table 1 EM data collection, data processing, model refinement and validation

From: Structure of the mechanically activated ion channel Piezo1

  1. *Particles are C3-symmetry expanded (triplicated, adding 120° or 240° to first Euler angle from unmasked asymmetric refinement, then classified with mask around single blade before refinement).
  2. †EMRinger score calculated for ‘inner core’, which includes Piezo repeat A, the anchor, inner helix, outer helix, CTD and latch domains.