Extended Data Figure 8: Subiculum conditional knockout plots.
From: Teneurin-3 controls topographic circuit assembly in the hippocampus
a, b, Plots from Ten3WT (a) and Ten3fl/fl (b) mice with minimal GFP–Cre expression. Heatmaps show normalized PHA-L fluorescence intensity (red, left) and normalized GFP–Cre intensity (green, middle) in subiculum, same mice. Each row is one section, 120 μm between rows, colour bars shown below a, and proximal–distal position is on the x axis. Surface plots are to the right of the corresponding heatmaps, showing PHA-L fluorescence intensity as height and GFP–Cre fluorescence intensity according to the colour map shown below a. P, proximal; D, distal; M, medial; L, lateral. Projections are similar between Ten3WT and Ten3fl/fl. c, d, Plots from Ten3WT (c) and Ten3fl/fl (d) mice with high GFP–Cre expression in subiculum. In Ten3fl/fl mice, PHA-L signal is decreased in GFP–Cre regions. Number of mice shown in Fig. 4.
