Figure 5: Genomic instability and recurrent copy-number alterations.
From: The landscape of genomic alterations across childhood cancers
a, Frequency of structural variants (SVs) across cancer types (n = 539 tumours). b, Structural variant load from a across all tumours in relation to TP53 mutations (generalized linear model, confidence interval 0.95). a, b, Quartiles, range of whiskers: 1.5 × interquartile range. c, Genomic regions with significant copy-number changes (red, gains or amplifications; blue, deletions; n = 516 tumours).
